Chikara Goto Selected Research

Sublingual Administration

4/2007	Sarpogrelate hydrochloride, a selective 5-HT2A antagonist, improves vascular function in patients with peripheral arterial disease.
1/2005	Vascular function in patients with lower extremity peripheral arterial disease: a comparison of functions in upper and lower extremities.
5/2002	Severity of hypertension affects improved resistance artery endothelial function by angiotensin-converting enzyme inhibition.

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Chikara Goto Research Topics

Disease

10	Hypertension (High Blood Pressure) 06/2022 - 05/2002
7	Atherosclerosis 07/2019 - 05/2003
5	Cardiovascular Diseases (Cardiovascular Disease) 10/2020 - 12/2006
4	Type 2 Diabetes Mellitus (MODY) 04/2022 - 01/2019
4	Hyperemia 01/2019 - 05/2002
4	Essential Hypertension 04/2015 - 02/2002
3	Adenoma (Adenomas) 11/2020 - 04/2015
2	Hyperaldosteronism (Conn Syndrome) 01/2019 - 04/2015
2	Ischemia 01/2013 - 03/2004
2	Periodontitis 10/2009 - 02/2008
1	Isolated Systolic Hypertension 04/2022
1	Hypotension (Low Blood Pressure) 01/2021
1	Diabetes Mellitus 11/2019
1	Coronary Artery Disease (Coronary Atherosclerosis) 01/2019
1	Pathologic Constriction (Stenosis) 01/2018
1	Acute Coronary Syndrome 10/2015
1	Myocardial Infarction 04/2014
1	Heart Failure 04/2014
1	Stroke (Strokes) 04/2014
1	Cerebrovascular Disorders (Cerebrovascular Occlusion) 12/2013
1	Coronary Disease (Coronary Heart Disease) 12/2013
1	Glucose Intolerance 06/2010
1	Chronic Limb-Threatening Ischemia 01/2010
1	Peripheral Arterial Disease 04/2007
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 02/2007
1	Body Weight (Weight, Body) 04/2002
1	Pheochromocytoma 02/2002

Drug/Important Bio-Agent (IBA)

7	rho-Associated KinasesIBA 01/2019 - 05/2003
7	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2013 - 02/2002
5	Vasodilator Agents (Vasodilators)IBA 01/2013 - 02/2002
4	Nitroprusside (Sodium Nitroprusside)FDA LinkGeneric 01/2013 - 03/2004
3	Hypoglycemic Agents (Hypoglycemics)IBA 04/2022 - 01/2019
3	AldosteroneIBA 11/2020 - 04/2015
3	Biomarkers (Surrogate Marker)IBA 12/2016 - 12/2013
3	Nitroglycerin (Dynamite)FDA LinkGeneric 04/2007 - 05/2002
3	Isosorbide Dinitrate (Isordil)FDA LinkGeneric 12/2002 - 02/2002
2	Coffee FDA Link 06/2022 - 04/2019
2	Hemoglobins (Hemoglobin)IBA 04/2022 - 10/2020
2	Antihypertensive Agents (Antihypertensives)IBA 04/2022 - 01/2019
2	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 12/2013
2	Eplerenone (Inspra)FDA LinkGeneric 11/2020 - 01/2019
2	CholesterolIBA 12/2013 - 04/2002
2	sarpogrelateIBA 01/2010 - 04/2007
2	C-Reactive ProteinIBA 10/2009 - 02/2008
2	Interleukin-6 (Interleukin 6)IBA 10/2009 - 02/2008
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2009 - 05/2002
1	lipoprotein cholesterolIBA 01/2021
1	Mineralocorticoid Receptor AntagonistsIBA 11/2020
1	Dipeptidyl-Peptidase IV InhibitorsIBA 11/2019
1	alogliptinIBA 11/2019
1	Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)IBA 11/2019
1	HDL CholesterolIBA 07/2019
1	hydroxyhydroquinone (hydroxyquinol)IBA 04/2019
1	AcidsIBA 04/2019
1	saxagliptin FDA Link 01/2019
1	4-(2'-pyridyldithio)benzyldiazoacetate (PPDA)IBA 01/2018
1	A-factor (Streptomyces)IBA 12/2016
1	Advanced Glycation End ProductsIBA 01/2015
1	Indicators and Reagents (Reagents)IBA 04/2014
1	Myosins (Myosin)IBA 01/2011
1	fasudil (AT 877)IBA 01/2011
1	Myosin-Light-Chain PhosphataseIBA 01/2011
1	Pioglitazone (Actos)FDA Link 06/2010
1	DiureticsIBA 11/2008
1	CalciumIBA 11/2008
1	Serotonin 5-HT2 Receptor AntagonistsIBA 04/2007
1	Carvedilol (Coreg)FDA LinkGeneric 02/2007
1	Caffeine (No Doz)FDA LinkGeneric 12/2006
1	imidaprilIBA 05/2002
1	Nitric Oxide Synthase (NO Synthase)IBA 05/2002
1	Amlodipine (Norvasc)FDA LinkGeneric 05/2002
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 05/2002
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 05/2002
1	omega-N-Methylarginine (NG Monomethyl L Arginine)IBA 05/2002
1	Insulin (Novolin)FDA Link 04/2002
1	LDL CholesterolIBA 04/2002
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 02/2002

Therapy/Procedure

3	Therapeutics 01/2019 - 02/2008
3	Sublingual Administration 04/2007 - 05/2002
2	Adrenalectomy 11/2020 - 02/2002
1	Percutaneous Coronary Intervention 04/2014
1	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 04/2014
1	Caloric Restriction 04/2002
1	Intra-Arterial Infusions 04/2002